MyBCTeam

Yes, bone loss is a known side effect of anastrozole and other aromatase inhibitors. Because these medications lower estrogen levels, they can reduce bone density over time — first leading to osteopenia (early bone thinning), and potentially progressing to osteoporosis (brittle bones).

Research also suggests that Show Full Answer

Yes, bone loss is a known side effect of anastrozole and other aromatase inhibitors. Because these medications lower estrogen levels, they can reduce bone density over time — first leading to osteopenia (early bone thinning), and potentially progressing to osteoporosis (brittle bones).

Research also suggests that anastrozole may be more closely linked to bone fractures compared to other aromatase inhibitors, so your doctor is right to take this seriously and monitor it closely. Prolia (denosumab) is a medication commonly prescribed to help protect bone density in people on aromatase inhibitors. Many MyBCTeam members have discussed their experiences with it.

Some things worth knowing before starting Prolia:

- It's given as an injection every 6 months
- It can help slow bone loss caused by hormone therapy
- Some people report side effects like joint or muscle pain
- It's important not to stop Prolia suddenly without talking to your doctor, as this can temporarily increase fracture risk

It's always a great idea to ask your oncology team about what to expect and how your bone density will be monitored while on it. You're definitely not alone in navigating this!

 AI-generated responses are not a substitute for medical advice. These services are not intended to diagnose, treat, or cure any condition or disease. Always ask your doctor about specific health concerns.

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