All cases are different, and you have to think about your own circumstances. I think how your body adapts to prolia depends a lot on the condition of your body and your bone density post-chemo. After chemo, I had developed osteopenia in the small of my back, although bone density was fine everywhere else. I opted for taking 5,000 IUs of Vitamin D daily because I didn't like what I read about the side effects of prolia and I was already prescribed 5 years of anastrozole, which came with its own batch of pain and discomfort. A woman in my local support group started with the prolia, along with her 5-year anastrozole, and the bone and joint pain was so bad that she could barely walk. She stopped taking the shots last fall, and she's much better, but she does have to take the daily doses of Vitamin D also.
Remember that it's your body and your decision. If you decide to try it, especially if your oncologist thinks it's your best option, you can also decide to stop if the discomfort is a problem.

blackrose I've been on Prolia for several years now and haven't suffered any negative effects. In fact, my osteoporosis is now osteopenia. Wishing you the best of luck in whatever treatment you choose.

Last week I had another bone density scan. My bone density is in the normal range now, after osteopenia two years ago and osteoporosis four years ago. The Prolia shot has definitely helped me.

I started Prolia a year ago, so far everything is going ok. I am a little nervous regarding whenever I have to have major dental work, though.

I, too, was nervous about Prolia after reading all the negative effects.I have been on it for three years with no side effects. My bone density has improved from osteoporosis to osteopenia. Maybe try it and see how it works for you - you can always stop!