How has Fosamax worked for managing bone density while on anastrozole?
You're right to be concerned about bone health while taking anastrozole. Aromatase inhibitors like anastrozole can weaken bones and increase the risk of osteoporosis and fractures because they reduce estrogen, which normally helps slow bone breakdown.
I was diagnosed with stage II ILC of the pleomorphic type in 10/2019 of the right breast and had a mastectomy in 12/2019. I have been on anastrozole since 01/2020. I have had a DEXA scan each year. Initially I was osteopenia and was taking vitamin D and calcium and walking 2 miles daily but by 2024 I was diagnosed with osteoporosis in the lower spine. Of the options given I chose to get Prolia shots every 6 months. I didnt want to take another pill. My oncologist wanted me on Prolia a year before I actually started but I had some reluctance due to the side effects of the medication. The Prolia stories on the internet scared me. My dentist told me that there is a possibility if major dental work is needed that it could be a problem. I went to see an endocrinologist who would administer the Prolia and she gave me different options for treating osteoporosis including fosamax. I chose Prolia after reassuring me that Prolia was safe. I also talked to someone I knew on Prolia and she said she had no side effects. I found out that after 6 months Prolia is out of your system so any major dental work would be scheduled at that 6 month period. I started the shots in 2024 and so far so good. My bone density has improved and is back to osteopenia and I haven't had any side effects from Prolia. I just have to have some bloodwork done a month before each shot.
Great info!