Does a Ki-67 score of 89% indicate the cancer will return quickly or have a high recurrence rate?
A Ki-67 score of 89% is quite high and indicates that a large percentage of cancer cells are actively dividing. While a high Ki-67 score generally suggests more aggressive cancer behavior, it's only one piece of the puzzle Show Full Answer
Does a Ki-67 score of 89% indicate the cancer will return quickly or have a high recurrence rate?
A Ki-67 score of 89% is quite high and indicates that a large percentage of cancer cells are actively dividing. While a high Ki-67 score generally suggests more aggressive cancer behavior, it's only one piece of the puzzle when it comes to recurrence risk.
Your cancer care team will look at several important factors together to estimate your personal risk of recurrence:
* The type and molecular subtype of your breast cancer (like hormone receptor status or HER2 status)
* The stage of the cancer (tumor size, lymph node involvement, and spread)
* Cancer grade (how abnormal the cells look)
* Surgical margins
* Your age at diagnosis
These factors work together to create a more complete picture. For example, hormone receptor-positive cancers may respond well to hormone therapy even with a high Ki-67, while triple-negative breast cancer tends to be more aggressive regardless of Ki-67 levels.
You might want to discuss genomic testing with your oncologist, which can provide more personalized information about your recurrence risk and which treatments may work best for you.
November 14, 2025
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