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i have been taking Letrozole for 18 months and this muscle pain is recent

July 1, 2025
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A MyBCTeam Member

I have now changed to Mar brand name Letrozole. No pain, no side effects at all what a relief. I wish I would have figured this out months ago and avoided all the pain and having to take ibuprofen just to be able to walk.

September 13, 2025
A MyBCTeam Member

It is the “trade” of the brand of Letrozole i am taking. Iknow of 4 brand or trade names. ACH, MAR, NAT and APO . The 1st 2 i had no issues with NAT was the worst almost every side effect that was listed and continued leg pain with Apo. Back to Mar brand name and no side effects. I can only conclude there is a difference in how they are manufactured.
Have a great day…..

September 14, 2025
A MyBCTeam Member

Excuse me for asking what is mar brand ? I also take Letrozole (femara)
I also have leg pain and hip pain . I didn’t know there were so many types.

September 14, 2025 (edited)
A MyBCTeam Member

The issue seems to be the actual brand name the one I had when the pain started is no longer offered because of the side effects it is Nat brand currently on Apo similar problem not quite as bad will be going back to Mar brand and hopefully this will stop. Taking 2 extra strength Ibuprofen so I am able to walk. Helps a lot
So looking forward to going back to the Mar brand that I had no issues with. Hope this information helps

August 3, 2025
MyBCTeam

Muscle and joint pain are common side effects of letrozole. While some people experience this pain throughout their treatment, others have noticed their symptoms improve over time. One encouraging note is that some MyBCTeam members reported significant improvement after the first six months of treatment. Since your pain is Show Full Answer

Muscle and joint pain are common side effects of letrozole. While some people experience this pain throughout their treatment, others have noticed their symptoms improve over time. One encouraging note is that some MyBCTeam members reported significant improvement after the first six months of treatment. Since your pain is recent despite being on letrozole for 18 months, it's important to discuss these new symptoms with your healthcare provider. They may want to:
- Check your bone density
- Evaluate if this is related to the medication
- Consider if any adjustments to your treatment plan are needed
- Rule out other potential causes

This is particularly important as bone thinning can occur with letrozole use and may need monitoring.

July 1, 2025

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