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Real members of MyBCTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
June 29, 2025
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A MyBCTeam Member

For the most part, yes. I guess the longer you take them the longer the reverse but once estrogen comes back side effects reverse.

June 29, 2025
MyBCTeam

Do the symptoms of AIMSS (Aromatase Inhibitor-Induced Musculoskeletal Symptoms) completely disappear after hormone therapy?

AIMSS typically develops about two months after starting aromatase inhibitor treatment and reaches its peak around four months later. These symptoms can include joint pain affecting hands, knees Show Full Answer

Do the symptoms of AIMSS (Aromatase Inhibitor-Induced Musculoskeletal Symptoms) completely disappear after hormone therapy?

AIMSS typically develops about two months after starting aromatase inhibitor treatment and reaches its peak around four months later. These symptoms can include joint pain affecting hands, knees, back, hips, and shoulders, along with muscle weakness and stiffness. While the search results don't directly address long-term outcomes after stopping treatment, it's important to note that these symptoms can be severe enough that about 20% of people stop their aromatase inhibitor treatment due to joint pain. If you're experiencing significant discomfort, speak with your doctor about pain management options or alternative therapies - but never stop taking medications without consulting your healthcare team first.

June 29, 2025

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