While your specific combination of hormone receptor status is less common, Luminal B breast cancers occur in about 15-20% of breast cancer cases. Luminal B cancers are typically characterized by being either ER-positive or PR-positive (in your case, PR-positive) and can be HER2-positive or negative (in your case, negative) Show Full Answer
While your specific combination of hormone receptor status is less common, Luminal B breast cancers occur in about 15-20% of breast cancer cases. Luminal B cancers are typically characterized by being either ER-positive or PR-positive (in your case, PR-positive) and can be HER2-positive or negative (in your case, negative). Luminal B cancers tend to be more aggressive than Luminal A types due to higher levels of Ki-67 protein, which affects how quickly cancer cells grow. Your treatment plan will be tailored to your specific hormone receptor status, taking into account that your cancer is PR-positive but ER-negative. Hormone therapy may be part of your treatment plan due to your PR-positive status.
May 23, 2025