Yes, it's possible to have characteristics that seem to indicate Luminal A but actually have Luminal B breast cancer. While your biomarkers (ER/PR positive, HER2 negative, and very low Ki-67) typically suggest Luminal A characteristics, genomic testing like MammaPrint can provide additional important information about your Show Full Answer
Yes, it's possible to have characteristics that seem to indicate Luminal A but actually have Luminal B breast cancer. While your biomarkers (ER/PR positive, HER2 negative, and very low Ki-67) typically suggest Luminal A characteristics, genomic testing like MammaPrint can provide additional important information about your specific tumor biology.
Luminal A breast cancers generally grow slowly and respond well to hormone-targeted treatments. Luminal B cancers, while sharing some characteristics with Luminal A, can be more aggressive in their behavior. The best approach is to discuss these seemingly conflicting results with your oncology team. They can explain how the MammaPrint results, along with your other biomarker information, will influence your specific treatment plan. Remember that these tests together help create a more complete picture of your unique cancer profile and guide the most appropriate treatment decisions.
February 27, 2025