Luminal B breast cancer is an aggressive subtype that occurs in approximately 15-20% of breast cancer cases. This type is characterized by being either
• Estrogen receptor (ER) positive or
• Progesterone receptor (PR) positive
And can be either HER2-positive or HER2-negative. What makes Luminal B cancers particularly Show Full Answer
Luminal B breast cancer is an aggressive subtype that occurs in approximately 15-20% of breast cancer cases. This type is characterized by being either:
• Estrogen receptor (ER) positive or
• Progesterone receptor (PR) positive
And can be either HER2-positive or HER2-negative. What makes Luminal B cancers particularly aggressive is that they have high levels of a protein called Ki-67, which helps cancer cells grow faster. The good news is that these cancers can be treated with HER2-targeted therapy along with other cancer treatments, depending on the specific characteristics of the tumor.
August 11, 2025