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Has anyone taken Keytruda and had bone loss? Have you had good or bad results from Keytruda?Dr doesn't want me to stop Keytruda yet it can cause osteoporosis. What I read on Reclast is mostly negative. So now I'm trying to figure out if I stay on Keytruda,will my bone lost get worst or could it have been from the other treatments. Also this was my first bone density test so don't know if I had bone lost before or after. All I know is I finished chemo in Feb, radiation in May and my bones started… read more

December 7, 2024
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Keytruda (Pembrolizumab) can potentially contribute to bone loss, as immune-related side effects may affect bone health. However, bone loss could also result from chemotherapy, radiation, or pre-existing conditions. Reclast (zoledronic acid) is a bisphosphonate used to strengthen bones and reduce fracture risk, but it may Show Full Answer

Keytruda (Pembrolizumab) can potentially contribute to bone loss, as immune-related side effects may affect bone health. However, bone loss could also result from chemotherapy, radiation, or pre-existing conditions. Reclast (zoledronic acid) is a bisphosphonate used to strengthen bones and reduce fracture risk, but it may have side effects like flu-like symptoms or, rarely, osteonecrosis of the jaw (ONJ). Discuss with your doctor the risks and benefits of continuing Keytruda and starting Reclast, as well as strategies to monitor and manage bone health.

December 7, 2024

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