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March 31
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A MyBCTeam Member

I was diagnosed with triple negative BC in 2022. I had 5 months of AC-T chemo then surgery, a lumpectomy, then 20 radiation treatments. I did 2 xeloda cycles but stopped because of side effects. I was stage 1 with no lymph node involvement. June 28 I will be 4 years out. 🙌.
Some people are a candidate for immunotherapy. I was not. It is an aggressive cancer so they hit it with everything they have. Treatment may have changed somewhat in the last four years. Ask any and every question you have to your oncologist.

March 31
A MyBCTeam Member

TNBC is an invasive, aggressive cancer that has no in markers. The only that feeds it is the body. Chemotherapy is the only thing that kills. The good news it does respond well to chemotherapy.
Current standard of care is Neo adjuvant chemo, chemo before surgery, Paclitaxel Carboplatin Pembrolizumab (immunotherapy for this type of cancer) every week times 12 followed by Adriamycin Cytoxan Pembrolizumab every 3 weeks times 4. That is 24 weeks of treatment. 4-6 weeks to recover before surgery, lumpectomy or mastectomy, what ever you decide with your doctor. Possibly followed by radiation. Radiation would be indicated for a lumpectomy, known positive lymph nodes, and/or and residual cancer found with surgery.

I was diagnosed with stage 1 TNBC, 1 cm, ki-67 85% in 2018. From biopsy to chemo chair was 3 weeks. I got AC and Taxol. Part way through my treatment, standard of care added Carbo and Pembro. I begged my doc to add it in, but he said he couldn’t. I was so fortunate to get complete pathological response, chemo killed all the cancer.
Did I love chemo, but I looked at it as this is temporary, the goal is curative, I can do this. I worked as an inpatient nurse during treatment. I had fatigue and nausea, but never vomited.

If your surgeon wants to take you to surgery first, I would run to a second opinion. Chemo can be started fairly quickly. If your doctor surgery, that can take a few weeks to get scheduled, plus recovery/healing can take time. Best case scenario, chemo could start 3-4 weeks after surgery. If there was just 1 tiny cancer cell that was not enough to show on imaging, that snuck out, it was now given 6-8 weeks to grow and spread. If there are healing complications, treatment gets pushed out even longer. After 12 weeks from surgery, chemo is no longer recommended. Now there is nothing to stop it.

Not trying to scare you, but I think people should make an informed choice.
I am approaching 7 years out from treatment, no evidence of cancer. I know how lucky I am!

Wishing you well!

March 31
MyBCTeam

What is triple-negative breast cancer?

Triple-negative breast cancer (TNBC) is a type of breast cancer where the cancer cells test negative for three key proteins:

- Estrogen receptor (ER)
- Progesterone receptor (PR)
- Human epidermal growth factor receptor 2 (HER2)

Because these proteins are missing, TNBC doesn't Show Full Answer

What is triple-negative breast cancer?

Triple-negative breast cancer (TNBC) is a type of breast cancer where the cancer cells test negative for three key proteins:

- Estrogen receptor (ER)
- Progesterone receptor (PR)
- Human epidermal growth factor receptor 2 (HER2)

Because these proteins are missing, TNBC doesn't respond to hormone therapies or HER2-targeted treatments that work for other breast cancers. This makes it harder to treat, but there are still effective treatment options available.

TNBC accounts for about 10-15% of all breast cancer cases and tends to grow more quickly than other types. It's more common in women under 40, and in Black or Hispanic women. How is TNBC typically treated?

Most people with TNBC receive a combination of treatments:

Chemotherapy is the main treatment and may be given:
- Before surgery (neoadjuvant therapy) to shrink the tumor
- After surgery (adjuvant therapy) to eliminate remaining cancer cells
- Common drugs include platinum-based medications like cisplatin and carboplatin

Surgery options include:
- Lumpectomy (breast-conserving surgery)
- Mastectomy (removal of the breast)

Radiation therapy is often used after surgery to target any remaining cancer cells.

Many MyBCTeam members with TNBC have shared their experiences with these treatments. The specific approach depends on the cancer's stage and individual circumstances. Your oncologist can discuss which combination would work best for your situation.

March 31

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