My Letrozole is Accord brand. I have been on it for about 1.5 months, so it’s the only manufacturer I have tried so far. I definitely have fatigue in the afternoon. I had a few hot flashes the first couple of weeks but they seem to have gone away. I do have some insomnia as a general rule, that seems worse. Some small headaches. Some joint/muscle aches in my back and hip. Some mood swings that could easily be from all my various health challenges I am sad/resentful about, but seem exacerbated. I don’t love it, but so far it’s not intolerable, especially if it’s potentially saving my life.

There is only one manufacture for Femara that is Novartis. UK Ltd
As for the generic letrozole there are 5 manufactures.
AAH Ltd
Accord UK Ltd
Alliance Healthcare Distribution Ltd
Amarox Ltd
Bristol Laboratories Ltd.
Why is there a shortage of letrozole?
Answer: Disruption of the manufacture of the drug.
The ingredients in Femara and the generic letrozole you can do a search of the ingredients in each of them.
You might also maybe get the manufactures patient data sheet on effects etc.
I get a product patient sheet with every bottle of my letrozole and it contains everything from studies done etc.

I was on it for nearly 3 years and had no side effects. I was also on ibrance during that time. They quit working and I have moved on to a couple different drugs. I have no idea who the manufacture was.

I was on that pill for 8 yrs. Unfortunately all these pills have side effects depending upon which one u’re taking. Unfortunately I had to get off that pill cause it wasn’t helping and I graduated to a chemo pill. The cancer came back after 8 yrs. So at least it’s not aggressive.I still take an estrogen inhibitor plus the chemo pill. Anyway I’m ok. I don’t have the pill anymore so I don’t know who’s name was on it. Anyway be well Mary

That’s pretty much what I have except for being tired an muscle pain right now that’s all I can reall think if