The AIs, CDK inhibitors, and chemo can all mess with your liver test numbers. I'm sure some of the other drugs/treatments for HER2+ and triple negative breast cancers also have liver side effects. I'm on the lowest dose possible of my AI which is Letrozole and CDK inhibitor which is Ibrance. Both chemo and Ibrance elevated my liver test results quite a bit. There's been studies done on the AIs that show most women will receive an adequate amount of benefit while taking the lowest sized dose. Some women even take their AI every other day and that seems to help too with all the nasty side effects. Talk to your doctor and see if a lower dose is possible or if changing to a different AI might help to bring your liver test numbers down closer to the normal range. Good luck ❤️
Elevated liver enzymes are something to be aware of when taking Aromasin (exemestane). While serious liver problems are considered rare, they are a known risk worth watching for.
Signs that something may be off with liver function include:
- Yellowing of the eyes or skin (jaundice)
- Pain or swelling in the abdomen
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