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Real members of MyBCTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
August 17
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A MyBCTeam Member

From what I have been told and read, Signatera is not FD approved for breast cancer. Not sure how they apply the results

August 17
MyBCTeam

That sounds really unsettling, and it's completely understandable to feel scared. A low positive on a second Signatera test after a negative first result is something worth discussing closely with your oncologist.

While the search results don't contain specific experiences with the Signatera test, false positives do occur Show Full Answer

That sounds really unsettling, and it's completely understandable to feel scared. A low positive on a second Signatera test after a negative first result is something worth discussing closely with your oncologist.

While the search results don't contain specific experiences with the Signatera test, false positives do occur with various breast cancer screening and monitoring tests. For example, breast MRIs and other imaging tools can produce false positives, meaning a test may suggest something concerning when cancer isn't actually present.

A few important things to keep in mind:

- A single low positive result doesn't automatically confirm cancer recurrence
- Results can vary between tests for a number of reasons
- Your oncologist may recommend additional testing to clarify what the result means
- Getting a second opinion on any concerning result is always a valid option

One MyBCTeam member shared that after seeking a second opinion, their diagnosis was actually changed to a less serious type, which led to a better prognosis.

The most important next step is to talk with your care team as soon as possible. They can help put the result in context and decide whether further testing is needed. You don't have to sit with this fear alone — lean on your support network while you wait for answers. 💙

August 17

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