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Diagnosis was stage 1 grade 2 estrogen and progesterone receptor positive, hers2? negative, with no lymph node involvement. I was also diagnosed with DCIS and LCIS. I had a partial mastectomy and 3 weeks of radiation treatment before starting the anastrozole. I also had stage 3 lung cancer with chemo and radiation to the same side and area as the breast cancer 7 years prior.

August 13
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A MyBCTeam Member

Thank you, I will talk with him about it. I'm so sorry to hear that you have been through it so many times. My prayers are with you.

August 14
A MyBCTeam Member

That's a question for your oncologist. Realistically though you are a 2 time cancer patient so your odds might be higher than if you never had both lung and breast cancer. That's how it is for me. I'm a 6 time cancer patient now. Twice with breast and 4 times with endometrial so I'm higher risk for new cancers. In my case the question is when, not if I will get csncer again. Talk to your doctor about it. Maybe another AI will agree with you better or a lower dose of the one you are taking now.

August 14
MyBCTeam

That's a really important question, and given how complex your medical history is, it deserves a thoughtful answer. Unfortunately, there's no simple percentage that can be given here β€” the risk of recurrence if stopping anastrozole early depends on many individual factors that only your oncologist can properly assess.

What Show Full Answer

That's a really important question, and given how complex your medical history is, it deserves a thoughtful answer. Unfortunately, there's no simple percentage that can be given here β€” the risk of recurrence if stopping anastrozole early depends on many individual factors that only your oncologist can properly assess.

What is known generally is that anastrozole is typically recommended for 5 years or more for hormone receptor-positive breast cancer. It has been shown to reduce recurrence risk by around 30% more effectively than some alternatives in postmenopausal women. Stopping early at 9 months would mean missing most of that protective benefit.

Your specific situation has several layers that make this especially important to discuss with your care team:

- Stage 1, Grade 2, ER/PR positive, HER2 negative β€” generally a lower-risk profile, but hormone therapy is still strongly recommended
- DCIS and LCIS present β€” these add complexity to recurrence risk assessment
- Partial mastectomy plus radiation β€” standard treatment, but margins and response matter
- Prior treatment to the same area β€” this is a significant factor your oncologist needs to weigh carefully The reason for wanting to stop anastrozole also really matters. If side effects are driving this decision, it's worth knowing that switching to another hormone therapy like tamoxifen or letrozole may be an option rather than stopping altogether.

A MyBCTeam member shared: *"Anastrozole and its alternatives make it very hard to lose weight. I've tried unsuccessfully for two years."* β€” side effects are real and valid, and many people do revisit their treatment plan.

Please have an open conversation with your oncologist before stopping. Given your unique history, they may want to consult with a specialist to give you the most personalized guidance possible. You deserve a plan that balances both protection and quality of life. πŸ’›

August 13

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