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A MyBCTeam Member asked a question 💭

I have been on both drugs for almost two years now.In hoping to stop the Verzenio in the summer for a knee revision. How are others doing years after taking these drugs?Is anyone out there like me on it for 2 years. My doctor said two years for the verzenio and ten for the Letrozole.

March 26
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A MyBCTeam Member

This is my 2nd time with breast cancer. I'm on Letrozole for the rest of my life due to aggressive hormone positive stage 3c breast cancer and on Ibrance for 3 years.

March 27
MyBCTeam

How are people doing after taking Verzenio and letrozole for extended periods?

It sounds like you're planning ahead for your knee revision, which is smart. Your treatment timeline—two years for Verzenio and ten for letrozole—is a common approach for certain breast cancer types.

Many MyBCTeam members have shared their Show Full Answer

How are people doing after taking Verzenio and letrozole for extended periods?

It sounds like you're planning ahead for your knee revision, which is smart. Your treatment timeline—two years for Verzenio and ten for letrozole—is a common approach for certain breast cancer types.

Many MyBCTeam members have shared their experiences with these medications over time. Some find that side effects improve after the first several months as their bodies adjust. One member noted that around the four- to six-month mark on letrozole, their body finally adjusted and side effects became more manageable with regular exercise and stretching.

Common side effects people experience with these medications include:

Verzenio:
- Diarrhea (most common)
- Hair thinning or loss
- Fatigue
- Nausea
- Low white blood cell counts

Letrozole:
- Joint and muscle pain (affects about 1 in 3 women)
- Hot flashes
- Bone density loss
- Hair thinning (about 6% of users)
- Sleep disturbances
- Dry skin

Some members have found that switching between similar medications can help if side effects become too difficult. Others have managed symptoms through lifestyle adjustments like staying active and maintaining a healthy diet.

It's great that you're coordinating with your doctor about pausing Verzenio for your surgery. They can help you navigate the timing safely.

March 26

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