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Real members of MyBCTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Anyone on letrozole

A MyBCTeam Member asked a question 💭
Port St. Lucie, FL
January 20
 · 
Reactions
A MyBCTeam Member

I was on Anastrozole and Exemestane; bad side effects. Now on Letrozole; 1 week. Hopefully better. The other 2 began problems at 2-3 months; extreme joint pain felt like torn rotator cuff and constant diarrhea with the other.

February 16
A MyBCTeam Member

I'm on Letrozole and my only side effect so far is hot flashes. I've been told since this is my 2nd estrogen positive breast cancer and it's a very aggressive one this time around that I will need to be on an AI for the rest of my life. If you do end up having too many bad side effects from Letrozole there are several other AIs you can try that may work better for you. Good luck ❤️

January 21
A MyBCTeam Member

On letrozole with no side effects.

January 20
A MyBCTeam Member

Yes, it works for me! Had DCIS Stage 1 right beginning summer. So instead of immediate surgery (lumpectomy/partial masectomy) dr. put me on letrozole as it was beginning of summer and reasons I wanted to be in sun. So I did pill for two months, it actually SHRUNK TUMOR like .1 cm a month, but so slow I thought better get it removed! So did end July. But on letrozole for another 3-1/2 years as never went off it, tho could have during chemo but never did. Sure, have a few aches in cold weather, but is it maybe just old age? (I'm 70). I swear by it, though!

January 20
MyBCTeam

Are you currently taking letrozole or considering it?

Many MyBCTeam members take letrozole (Femara) for hormone receptor-positive breast cancer. It works by reducing estrogen levels in the body, which helps prevent certain cancer cells from growing.

Members share a wide range of experiences with this medication. Some Show Full Answer

Are you currently taking letrozole or considering it?

Many MyBCTeam members take letrozole (Femara) for hormone receptor-positive breast cancer. It works by reducing estrogen levels in the body, which helps prevent certain cancer cells from growing.

Members share a wide range of experiences with this medication. Some common side effects people report include:

- Joint and muscle pain (almost half of people experience this)
- Hot flashes
- Fatigue
- Sleep problems
- Bone thinning
- Hair loss and dry skin
- Digestive issues

The good news is that many members find their side effects improve over time. One member shared that after six months, their significant leg and hip pain got much better. Another noted that around the four- to six-month mark, their body adjusted and side effects became more manageable.

Some members find relief through regular exercise, stretching, staying hydrated, and eating a balanced diet. If side effects become too difficult, your healthcare provider can discuss alternatives or ways to manage symptoms better.

What specific concerns or questions do you have about letrozole?

January 20

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