I'm taking Ivermectin and mebendazole. I think there is a couple others taken it but can't remember which pink sisters. I have been on it since around December 2024. So far it is working for me. Hugs
@A MyBCTeam Member.....I went to the laundromat yesterday so I had some time to kill. While I was there I read everything you posted above and spent about 4-5 hours total yesterday researching Ivermectin use for cancer on reputable web sites. I also researched Dr. Lee and Mr. William (Viliam) Makis.
Regarding Ivermectin (IVM), from what I learned it is too soon to know based on research to date if it will be effective or safe to use in humans to fight cancer. The majority of studies are early phase 1 or 2 studies conducted in petri dishes, test tubes, and on lab mice/rats. The doses of IVM that are used are quite high and most likely toxic if used at the same dosages in humans (nausea, vomiting, dizziness, liver toxicity, seizures, blindness, coma, death, interaction with blood thinners and chemo drugs potentially altering their efficacy, etc.). There was one phase 2 study done on 12 triple negagative breast cancer patients where IVM was used with immunotherapy. The results did not show any benefit from IVM and were the same as if IVM was not included along with the immunotherapy. There is another phase 2 study going on now that also involves triple negative breast cancer patients and the results should be out sometime in 2026. There have been no phase 3 studies done yet on humans. These are the large studies done on multiple people when drugs/treatments have passed initial studies and are being considered for human use. Essentially everything I read says there is promise for Ivermectin, but large scale human studies are needed, the required dosage of IVM may be toxic to humans, and future use of IVM, if deemed safe and effective, would probably consist of IVM being used in conjunction with chemotherapy and/or other mainstream cancer treatments. The only FDA approved usage of IVM in humans is as an anti-parasitic and it is not effective against Covid as claimed during the pandemic.
Dr. Lee has excellent credentials, training, and went to top notch schools to earn his medical degree. If I still lived in California I might consider seeing him because of his reputation and because he practices traditional oncology in addition to his research. Since he is doing research on IVM I know that's a big plus for you and he's fairly local to you as well. I think it would be a great idea for you to make a consultation/2nd opinion appointment with Dr. Lee if he is accepting new patients.
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Next we tested if Ivermectin synergized with an immune-based treatment such as anti-PD1. The combination of Ivermectin and anti-PD1 drugs showed good activity. We also used Ivermectin alone as a control and found that Ivermectin was actually triggering an immune response as shown by the presence of immune cells in the tumor. However Ivermectin by itself was insufficient to stop the growth of existing tumors. We were not surprised because an established tumor has already put in place mechanisms to block the immune response. (There are also other reasons why Ivermectin alone may not work in established cancers). However I thought, what if we give Ivermectin in a preventive setting before tumors are fully developed? Could we induce enough immunogenic death of growing cancer cells to auto-vaccinate people against the cancer? That is the hypothesis I wanted to test. I was fortunate and thankful to CPI for funding this research. We knew we had limited time and resources so we had to go with a spontaneous cancer model that gives tumors within weeks to months. This is not ideal because in humans, tumors can take many years to develop, but this cancer model was helpful to determine if the idea is worth pursuing. We found that Ivermectin had a significant effect in delaying cancer development. This is a promising start. Because Ivermectin is already an inexpensive, safe drug, it could be a very practical way to prevent cancer, even in emerging countries.
Here is a little AI info on Ivermectin:
Several preclinical studies have demonstrated that ivermectin exhibits anticancer effects across various cancer types. Research shows that ivermectin induces immunogenic cancer cell death and enhances T cell infiltration into breast tumors, demonstrating synergy with immune checkpoint blockade in mouse models.
Another study found that ivermectin, when combined with recombinant methioninase (rMETase), synergistically eradicated MiaPaCa-2 pancreatic cancer cells in vitro, with the combination reducing cell viability by 80% compared to 45% with ivermectin alone.
In colorectal cancer, ivermectin was shown to inhibit cell growth in SW480 and SW1116 cell lines by promoting reactive oxygen species (ROS)-mediated mitochondrial apoptosis and inducing S phase cell cycle arrest.
Additionally, ivermectin has been found to reverse multidrug resistance in cancer cells by inhibiting the EGFR/ERK/Akt/NF-κB signaling pathway, thereby reducing P-glycoprotein expression and enhancing the efficacy of chemotherapeutic agents.
These findings suggest that ivermectin may have broad-spectrum antitumor potential, particularly in combination with other therapies.
Ivermectin induces immunogenic cell death and enhances T cell infiltration in breast cancer models, showing synergy with anti-PD1 therapy.
The combination of ivermectin and rMETase synergistically kills pancreatic cancer cells (MiaPaCa-2) in vitro.
Ivermectin inhibits colorectal cancer cell proliferation through ROS-mediated apoptosis and S phase arrest.
Ivermectin reverses drug resistance in cancer cells by targeting the EGFR/ERK/Akt/NF-κB pathway and downregulating P-glycoprotein.
Dr. Peter P. Lee and colleagues are preparing a human clinical trial based on promising results in mice.
AI-generated answer. Please verify critical facts.
The AIs and CDKs have been more rigorously tested and used by humans and the good effects they provide from a medical and scientific standpoint statisically outweigh the negative side effects for most people. That doesn't mean they are a pleasure to take because so many people have side effects they can't tolerate and switch or stop taking these meds altogether. Despite this they are still scary meds to take, just like most other cancer meds are. At least they have more medical and scientific research on proper dosing and side effects than the anti-parasitics. To me I feel a little safer knowing the research has gone further and knowing the various odds/statistics of this, that, and the other benefits and side effects. Maybe it's the gambler in me, I like good odds. 🎰🎲♣️
For those that are taking the anti-parasitics, yes, your are doing a service and being pioneers by using existing meds off label to seek out new and beneficial cancer treatments 👍 I just hope while you're out there doing your treatment, your way, that you are least part of a study so your pioneering spirit and contributions are counted towards progress, good or bad, that you are montitored closely for safety purposes, and your results are benificial to you in the long term ❤️