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Real members of MyBCTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
November 17, 2025
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A MyBCTeam Member

Thank you so much! I go in tomorrow so I’ll ask.

November 17, 2025
A MyBCTeam Member

Your biopsy pathology should list the bio markers: Estrogen Progesterone Her2. ER and PR are hormones, Her2 is an epithelial protein.
ER/PR+ Her2- is hormone positive. ER/PR+ Her2+ is triple positive. ER/PR- Her2- is triple negative. ER/PR- Her2+ is Her2+.

November 17, 2025
MyBCTeam

How is triple-negative breast cancer identified through testing?

Your breast cancer subtype is determined through laboratory testing of tissue samples taken during a biopsy. When you have a biopsy, a doctor removes a small sample of tissue using a needle. This sample goes to a laboratory where a pathologist runs specific Show Full Answer

How is triple-negative breast cancer identified through testing?

Your breast cancer subtype is determined through laboratory testing of tissue samples taken during a biopsy. When you have a biopsy, a doctor removes a small sample of tissue using a needle. This sample goes to a laboratory where a pathologist runs specific tests on the cancer cells.

The tests look for three key proteins:
- Estrogen receptor (ER)
- Progesterone receptor (PR)
- Human epidermal growth factor receptor 2 (HER2)

If your cancer cells test negative for all three of these proteins, you have triple-negative breast cancer. If any of these proteins are present, your cancer is classified differently and may respond to hormone therapies or targeted treatments.

Your pathology report will show these test results along with information about your cancer's type, grade, and stage. This information helps your doctor determine which treatments are most likely to work for you.

If you'd like to share your diagnosis picture or discuss what your specific results mean, that might help provide more personalized guidance about understanding your subtype.

November 17, 2025

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