So the estrogen levels will never be like they were before starting the hormone therapy?
October 20, 2025
Yes, joint and muscle pain can persist after stopping aromatase inhibitors. These medications work by lowering estrogen levels, which can lead to long-term effects on bone density and joint health. Aromatase inhibitor-induced musculoskeletal symptoms (AIMSS) commonly affect areas like the hips, hands, knees, back, and Show Full Answer
Yes, joint and muscle pain can persist after stopping aromatase inhibitors. These medications work by lowering estrogen levels, which can lead to long-term effects on bone density and joint health. Aromatase inhibitor-induced musculoskeletal symptoms (AIMSS) commonly affect areas like the hips, hands, knees, back, and shoulders. Some ways to help manage ongoing joint pain include:
• Regular physical activity and stretching
• Physical therapy
• Weight management (higher BMI is associated with increased joint pain)
• Acupuncture
• Daily walking routines
It's important to discuss persistent pain with your healthcare team, as they can help develop an appropriate management plan for your specific situation.
October 20, 2025