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Real members of MyBCTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
September 17, 2025
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A MyBCTeam Member

I've been on letroz for a while now. My biggest issues are joint pain and weight gain. The joint pain comes and goes and I try to walk as much as possible around the stores and in the house. I did gain weight originally and can do so quickly if l dont eat properly. I did lose the weight but it took a long time to realize that I have to keep a food journal and lay off the chocolate. I'm short so every pound shows . Compared to other drugs, I prefer letrozole.. It can cause night sweats and affect your mood as well but we learn to handle those and move on. Everybody is different so letrozole affects each person differently. My friend is on letrozole and has more side affect than j do but she's also younger and going through menopause. My other friend has no issues with ketrozole at all. It's like taking an aspirin for her! She never gained an ounce, had hot flashes, or joint pain! Iam wishing you well and hoping you have no issues at all. We love you and we care!! Stay in touch. Endless hugs!!

September 17, 2025 (edited)
A MyBCTeam Member

My four-year battle with breast cancer involved numerous unsuccessful treatments, including chemotherapy, radiation, and natural therapies. I found a cure through the World Rehabilitate Clinic, which offers effective medication to eliminate cancer cells and treatments for conditions like hysterectomy issues and Alzheimer’s disease. Educate yourself about your diagnosis and explore options at the World Rehabilitate Clinic.

September 17, 2025
MyBCTeam

Common side effects of letrozole that you should watch for include:

• Joint, bone and muscle pain
• Hot flashes and night sweats
• Sexual side effects including vaginal dryness
• Hair thinning and dry skin
• Digestive issues like nausea or constipation
• Mood changes including anxiety or depression
• Changes in weight Many Show Full Answer

Common side effects of letrozole that you should watch for include:

• Joint, bone and muscle pain
• Hot flashes and night sweats
• Sexual side effects including vaginal dryness
• Hair thinning and dry skin
• Digestive issues like nausea or constipation
• Mood changes including anxiety or depression
• Changes in weight Many members have found these strategies helpful for managing side effects:

• Give your body 4-6 months to adjust to the medication
• Exercise and stretch daily to help with joint pain
• Stay hydrated and maintain a healthy diet with whole foods
• Consider working with a registered dietitian
• Report any serious symptoms like chest pain, blood clots, or severe allergic reactions to your doctor immediately

Remember that side effects can vary significantly between individuals. What works for one person may not work for another, so stay in communication with your healthcare team about any concerns.

September 17, 2025
A MyBCTeam Member

Hello. I have been on Letrozole for 2 years now. I started it at the same time as Verzenio so its hard for me to tell which side effects were from which drug. What I did finally do was switch to takjng it at bedtime so that the side effects might be muted by sleep.

September 18, 2025
A MyBCTeam Member

Hi Carrie sorry to hear about your complications but I am very interested in your therapies at world rehabilitate clinic? I hope you have found alternative things that are working for you. Where are you from? Is it very expensive?
I am having surgery 9/30. Bx DCIS grade 3. Larger area on MRI 3 cm.
I am very nervous and the waiting has been difficult. Blessings and prayers.

September 18, 2025

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