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A MyBCTeam Member asked a question 💭
Wake Forest, NC
August 20, 2025
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How does anastrozole affect breast size after mastectomy?

Anastrozole is an aromatase inhibitor that primarily affects hormone levels in your body. After a mastectomy, the breast tissue has been removed, so anastrozole would not directly affect breast size. However, some people may experience overall body weight changes Show Full Answer

How does anastrozole affect breast size after mastectomy?

Anastrozole is an aromatase inhibitor that primarily affects hormone levels in your body. After a mastectomy, the breast tissue has been removed, so anastrozole would not directly affect breast size. However, some people may experience overall body weight changes while taking anastrozole, particularly during the first year of treatment.

Risk factors for weight changes while taking anastrozole include:
• Being under age 60
• Having had a mastectomy
• Smoking cigarettes If you have concerns about changes in your body while taking anastrozole, it's important to discuss them with your healthcare team. They can help develop strategies to manage any side effects and ensure you're getting the most benefit from your treatment while maintaining your quality of life.

August 20, 2025

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