I started developing an itchy rash on my neck about 3 days after each chemo treatment and I just called it “chemo flush” because I thought it was a normal reaction…I used otc Cortizone 10 cream for acne on it to help and my primary doc said that was good.
Now I’m not so sure it was a “normal reaction” because after my third chemo treatment (3 of 4) I didn’t have the flush for 8 days but suddenly developed hives that ended up head to toe and had to go to the ER. The worst was on the palms of both hands. They said it was a reaction to the chemo and treated me with pill forms of allergy meds….including steroid, Benadryl, Pepcid (also used for allergic reactions)….
I still had issues with the palms of my hands and once the steroid wore off at home my throat started to hurt like at the strep throat level and swelled up which caused another trip to the ER where they treated me with the same meds only in IV form. It took 1 1/2 hrs laying in the ER before the IV meds kicked in and did a warm rush through my body ….and finally my palms quit itching and my throat quit hurting. I was not able to take my last chemo treatment since the next allergic occurrence might have been anaphylactic shock.
So pay attention to your rashes or any other reactions you’re not sure about during chemo…you know your body so have it checked out when you feel what’s happening isn’t “normal”. Better safe than sorry!

I got tiny scabs on my face that just showed up. My complexion was terrible during chemo.