It should take about a week to 10 days. For swelling hotflashes etc. To also lessen.

Sony, I sure hope any discomfort ends quickly. I’ll watch for the answers given on this site. Here’s a hug. 🤗

Have been on Letrozole now since Dec. but did reduce dose for 2 mos.; and no joint pains or side effects (some hot flashes) as my body is getting used to it. It is very effective, so that is why I opted to stay on it...even if it makes me cry a lot!

Woohoo! There’s light at the end of the tunnel

I really do not know!