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Real members of MyBCTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A MyBCTeam Member asked a question 💭
Fairfax, VA

I have been on anastrozole for 5 years, dealing with the side affects reasonably well. My oncologist wants me to switch to Letrozole for another 2 years. I am fearful that switching will make me gain weight (which I already did with anastrozole) in addition to having new side affects? Has anyone had experience with switching medicine after 5 years?

November 17, 2019
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A MyBCTeam Member

I switched from anastrozole after 11 months. The bone pain was intense. I now take exemestane. I have less pain, less hot flashes. It does affect my mood sometimes, but we have had a lot of outside stress going on in the family too. Do not have weight gain so far. However, I have thyroid issues (thanks to all of the treatments) and am experimenting with different medication.

December 11, 2019
A MyBCTeam Member

Did your MO say why you should make a switch at this time? Curious why a change at this point in time.
I requested a change from the anastrozole after 16 months. I was switched to Letrozole at that time. I was better able to cope with the side effects from the Letrozole vs the anastrozole.

November 17, 2019

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