I was on the menopause fence at 46 (youngish) before chemo and I have a history of blood clots from Factor 5 Leiden - so my Onc put me on arimadex/anastrozole with injections of Lupron every 3 moths to help shut down the ovaries. I do get bad hip pain - specially when I have to stand for a while - but I had pretty moderate hip pain before chemo (gymnastics and track/hurdles through college). I do get sore feet - pins and needles - specially when I first wake up in the morning and waddle to the bathroom. But after waddling down to the kitchen it starts to feel better.

Quality of life, not quantity. I could not take it any longer. With these "Cancer" pills. This medicine hurts my knees SO frigging bad I could barely walk!! I stopped. QUALITY of life is just too important for me. I'll take my chances. With surgery along with radiation was just inconvenience compared to this medicine. God Bless you all.

I tried all of them but tomixifan. I find anastrazole least pain but just started cymbalta for joint pain and it is helping immensely

Exemestane 25 mg. Any one with comments, experience, pain? A comments would be greatly appreciated. Thanks ladies.

I've been on @Arimidex over a year now. Between the nightly pill of @Arimidex and the Zometa infusion once a month (bone strengthening) I feel like I'm about 90 when I wake up in the morning - hands and feet achy. But, once I get across the room, I start to feel better and then that's it for the day. I can put up with that, as long as it keeps killing my cancer like it's been doing!
On the frustrating side of the Arimidex is the insomnia. The mega-menopause is not fun. Although that's the only problem (no hot flashes, etc.) but it's a bugger to deal with when I have to get up to go to work. I'm trying different things to deal with the insomnia.

The achiness and insomnia is bearable, cancer isn't.