I've been on it for 3.5 yrs and all I have is slight leg cramps at night sometimes

I stared at the bottle like it was a poisonous snake for two days before I finally took the first pill. I have been on Anastrozole for about 2 1/2 months and so far no joint pain! If that changes I will definitely post it, but from what I've read not everyone experiences joint pain from Anastozole (Arimidex). Good luck to you!

I was on it for 5 years with no joint pain.i wish you the same!

My bones started feeling fragile after 6 months on Femara, so my oncologist switched me to Aromasin. Very Expensive at $250 a month! Within a week I has severe joint and muscle pain, and after 3 weeks I could barely lift my arms, had to have help getting dressed, going to the bathroom, etc. I quit for 3 months and went on Vitamin D to build up my bones. My oncologist was going to put me on Tamoxifen for 4 years, but I said no. If the cancer comes back, at least I won't be a bedridden invalid.

Seven days into taking Anastrozole I woke up feeling like I had been hit by a freight train! Every joint in my body was affected; every tiny little finger and toe joint as well. I could barely get out of bed. I stayed with it for 3 months even though most mornings I would wet the bed or the floor because my body didn't work to get me out of bed and to the bathroom.

On Letrozole for a full year now, same exact side effects but now I have anti-inflammatory and Vicodin an hour before getting out of bed (I set my alarm for taking meds then another for getting up.) The pain and stiffness is still there but more tolerable. I tried taking my Letrozole varying times of day to effect fewer side effects to no avail.

I kept at it for a year because I didn't know what else to do. I stopped taking it a few days ago because I have very low quality of life. I am so amazed and envious of all the women who are not so affected. I am very happy for them!