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August 16
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MyBCTeam

Great question! Phesgo is a subcutaneous (under the skin) injection that combines trastuzumab (Herceptin) and pertuzumab (Perjeta) into one shot. Compared to the traditional IV infusion, which can take 30–90 minutes per drug, Phesgo takes only a few minutes to administer.

Clinical studies have confirmed that Phesgo is just Show Full Answer

Great question! Phesgo is a subcutaneous (under the skin) injection that combines trastuzumab (Herceptin) and pertuzumab (Perjeta) into one shot. Compared to the traditional IV infusion, which can take 30–90 minutes per drug, Phesgo takes only a few minutes to administer.

Clinical studies have confirmed that Phesgo is just as safe and effective as the separate IV infusions. The subcutaneous delivery means the medication absorbs through the fatty tissue under the skin rather than directly into the vein, but the therapeutic results are comparable. When it comes to side effects like nausea, both delivery methods share similar risks since the active ingredients are the same. Common side effects can include:

- Nausea
- Fatigue
- Body aches or weakness
- Numbness or unusual sensations
- Potential impact on heart function (regular heart monitoring is strongly recommended)

One MyBCTeam member described feeling "whole body numb, aching, weak" and experiencing "very weird sensations" during treatment.

It's really important to flag nausea or any other side effects to your oncology team — there are often ways to manage them so treatment stays on track. 💛

August 16

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