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A MyBCTeam Member asked a question 💭
Charlotte, NC

I’m about to start anastrozole. I’m also on biologics for Psoriatic Arthritis so I already suffer from joint pain and fatigue. Does anyone else have this double whammy?

July 18
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A MyBCTeam Member

I have lupus and rheumatoid arthritis. It was hard at first to determine what made me more tired. I have evened out now as far as fatigue. My joint pain was well managed before I started this adventure.

July 22
A MyBCTeam Member

Thank you for the info, hopefully I’ll be as lucky. My biologic, remicade doesn’t appear to be effective anymore so hopefully I’ll get this sorted before starting the anastrozole.🤞

July 22
MyBCTeam

Starting anastrozole when you're already dealing with joint pain and fatigue is genuinely tough — that "double whammy" feeling is very real and completely understandable.

Joint pain and stiffness are among the most common side effects of anastrozole, since it works by significantly lowering estrogen levels. So it's worth Show Full Answer

Starting anastrozole when you're already dealing with joint pain and fatigue is genuinely tough — that "double whammy" feeling is very real and completely understandable.

Joint pain and stiffness are among the most common side effects of anastrozole, since it works by significantly lowering estrogen levels. So it's worth having an honest conversation with your oncology team upfront about your existing joint issues, so they can monitor you closely and have a plan ready. Here are some strategies that may help manage joint pain and fatigue while on anastrozole:

- Regular gentle exercise — A MyBCTeam member who experienced pain and stiffness on anastrozole shared that walking 1.5 miles each evening left them pain-free after six months
- Bone density monitoring — Anastrozole can weaken bones over time, so your care team may recommend calcium, vitamin D, or bone-strengthening medications
- Weight management — Higher body weight can increase joint pain risk on anastrozole, so staying active helps on multiple fronts
- Open communication with your care team — They can adjust or add medications if side effects become hard to tolerate

You're not alone in navigating this. Many MyBCTeam members share similar experiences and have found ways to manage. Bringing your full health picture to your oncologist will help them tailor the best approach for you.

July 18

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