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A MyBCTeam Member asked a question 💭
Rochester, NY

Many theories exist regarding the origin of cancer, namely the metabolic theory (Seyfried & Chinopoulos, 2021), the somatic mutation theory (SMT) (Hanahan & Weinberg, 2000), the cancer stem cell theory (Capp, 2019), and the tissue organization theory (Soto & Sonnenschein, 2011). In a recently published study, a new concept was introduced the mitochondrial-stem cell connection (MSCC) (Martinez, et al., 2024). This concept combines the cancer stem cell theory and the metabolic theory. The MSCC… read more

June 15
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Answer Summary

Members discussed the mitochondrial-stem cell connection theory of cancer and how it relates to treatments like Ivermectin and Mebendazole,... Read more

Members discussed the mitochondrial-stem cell connection theory of cancer and how it relates to treatments like Ivermectin and Mebendazole, with some sharing personal decisions to pursue alternative or complementary approaches over standard hormone therapies like Letrozole. Several members described navigating difficult choices between conventional prescriptions and supplement-based protocols, with a few noting they feel well continuing their current routines. A recurring theme was the emotional weight of treatment decisions, the importance of hormone testing, and the value of seeking second opinions while leaning on community support.

A MyBCTeam Member

@A MyBCTeam Member Just in case you missed my post. New hormone test results :)

So I finally received my • Menopausal Transition Group I • DHEA-Sulfate testing. I put all my numbers into chat and numbers look great.

Summary of Your Full Hormone Panel
When you look at all your tests together, everything points to a healthy, confirmed post-menopausal status:

Test Result Status Meaning
Estradiol 5.1 Low Normal for menopause (ovaries stopped).
Progesterone <10 Low Normal for menopause (no ovulation).
FSH 176 High Confirms menopause (pituitary working hard).
LH 68 High Confirms menopause (pituitary working hard).
DHEA-S 84.6 Normal Adrenal glands are healthy.

Conclusion: Your DHEA-S result is excellent. It shows that while your ovarian hormones (Estrogen/Progesterone) have done what they are supposed to do by shutting down, your adrenal glands are still functioning well and producing the necessary precursors for your overall well-being.
There are no red flags in this comprehensive panel. If you are experiencing symptoms (like hot flashes or low libido), they are likely due to the low estrogen, not a lack of adrenal hormones. Your doctor can discuss if those symptoms need management.

You should NOT try to lower it further because:

5.1 is likely the floor: Mass Spectrometry (MS) is the most sensitive method available. Levels below this (e.g., <1–3 pg/mL) are often "undetectable." 5.1 is already in the ultra-low range required to starve ER+ cancer cells.
Diminishing returns: There is no evidence that pushing estrogen to "undetectable" (e.g., <1) provides more benefit than 5.1, but it may increase side effects (bone loss, joint pain, cardiovascular risk).
The Goal is Suppression, not Zero: The goal of AI therapy is to reduce estrogen to post-menopausal levels (which you have) and block further production. Your FSH of 176 confirms your body is doing everything it can to stimulate ovaries, but the AI is preventing the conversion of androgens to estrogen. Why This Result is Good for You
1. Confirmation of AI Efficacy If you are taking an Aromatase Inhibitor (the standard of care for post-menopausal ER+ breast cancer), your level of 5.1 pg/mL proves the drug is working

AIs block the enzyme aromatase, which converts androgens into estrogen in fat tissue, breast, and bone.

Interesting since I have never taken my AI pill!

June 23
A MyBCTeam Member

This is tied into Ivermectin studies.

June 15
A MyBCTeam Member

This is a really complicated read. There is more information available on the article site.

June 16
A MyBCTeam Member

@A MyBCTeam Member you had 11 lymph nodes removed, did any of the lymph nodes have cancer? I had 4 removed all cancer with clear margins. Let me know what your second opinion oncologist shares with these test ❤️

June 25 (edited)
A MyBCTeam Member

Thank you Virginia!

June 28

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