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A MyBCTeam Member asked a question 💭
Rochester, NY

Clinical Trial Opportunity

Researchers at Yale are enrolling participants with early stage ER+ breast cancer who have completed treatment. The study uses a ctDNA blood test to detect early signs of recurrence and improve patient outcomes.
ctdna newsletter(3)

GRASP cancer

ctDNA Guided Treatment for
Patients with ER+ Breast
Cancer Who Have Completed
Treatment
A ctDNA Blood Test for Cancer
This study aims to use a blood test (ctDNA) to find out which patients might benefit
from extra treatment… read more

February 16 (edited)
 · 
Reactions
A MyBCTeam Member

This is what KarenFischbeck posted a while ago about Signatera. Signatera is a personalized, blood-based molecular residual disease (MRD) test by Natera that detects circulating tumor DNA (ctDNA) to identify cancer recurrence up to two years earlier than imaging. It is tailored to a patient's specific tumor mutations, offering high sensitivity for monitoring cancer,, including colorectal, breast, lung, and bladder cancers. The test is covered by Medicare for various solid tumors, with financial assistance programs available. I just requested this from my Oncologist and had the blood drawn done a couple of days ago. They already have my tissue sample when I had my surgery.

February 17
A MyBCTeam Member

This sounds wonderful and I would do it if I qualified. Currently in a drug trial
for a c diff vaccine. I had exchange surgery last Dec., probably going to have a revision surgery in May or June. I was ER+, PR+, HER2-. if there is ever a clinical trial I can do in future years with those diagnosis parameters, I will. Everything helps our future generations.

February 16
MyBCTeam

Are you interested in learning about clinical trials for early-stage ER+ breast cancer that monitor for recurrence?

This Yale study sounds promising! It's using ctDNA (circulating tumor DNA) blood tests to catch early signs of recurrence in people who've finished treatment for early-stage ER+ breast cancer.

Here's what Show Full Answer

Are you interested in learning about clinical trials for early-stage ER+ breast cancer that monitor for recurrence?

This Yale study sounds promising! It's using ctDNA (circulating tumor DNA) blood tests to catch early signs of recurrence in people who've finished treatment for early-stage ER+ breast cancer.

Here's what makes this approach interesting:

Why ctDNA Testing Matters:
- It can detect cancer cells in your blood before symptoms appear
- Early detection may lead to earlier intervention and better outcomes
- It's a less invasive way to monitor for recurrence compared to imaging alone

About ER+ Breast Cancer:
ER+ (estrogen receptor-positive) breast cancer tends to grow in response to estrogen. While hormone therapy like tamoxifen helps lower recurrence risk, monitoring remains important since ER+ cancers can sometimes return even years after treatment.

Clinical Trial Benefits:
- Access to cutting-edge monitoring technology
- Close medical supervision and personalized care
- Contributing to research that helps future patients

If you're considering this trial, discuss it with your oncologist. They know your specific situation best and can help you weigh whether the potential benefits align with your needs.

February 16
A MyBCTeam Member

I haven’t had c diff, but was tagged/asked to be in the trial simply because of my high number of hospital & doc office visits. It puts us all in a higher risk bracket.
This isn’t the first ever c diff vaccine trial, but one that is using a different vaccine
“recipe” that will hopefully be more affective. Trial and error, then tweak, the story of medicine. (and life!)

February 17
A MyBCTeam Member

Hi @A MyBCTeam Member I am doing the Signatera test next month. I’m nervous & excited all in one to try it. My oncologist said that if my insurance doesn’t cover it, the signatera people usually won’t charge a patient then. I hope it’s true, I don’t need another Dr bill 😩.

February 20

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A MyBCTeam Member asked a question 💭
Wake Forest, NC