What are the chances of recurrence after early-stage DCIS with HER2-positive status, lumpectomy, and radiation?
Your treatment approach sounds solid. Having a lumpectomy followed by radiation therapy significantly reduces recurrence risk for DCIS. Generally, people who have a lumpectomy with radiation have up to a 15% Show Full Answer
What are the chances of recurrence after early-stage DCIS with HER2-positive status, lumpectomy, and radiation?
Your treatment approach sounds solid. Having a lumpectomy followed by radiation therapy significantly reduces recurrence risk for DCIS. Generally, people who have a lumpectomy with radiation have up to a 15% chance of relapse, compared to 25-30% with lumpectomy alone.
The HER2-positive aspect adds another layer to consider. HER2-positive breast cancer is associated with higher recurrence risk and tends to recur earlier - most commonly within the first five years after diagnosis. After targeted therapy, about 25% of people with HER2-positive breast cancer experience recurrence within 10 years.
Several factors can influence your specific risk:
- Tumor size and grade (high-grade DCIS has higher recurrence risk)
- Whether cancer cells were found in lymph nodes
- Your age at diagnosis
- Hormone receptor status
Since DCIS is noninvasive and you've had both surgery and radiation, your prognosis remains very good. People with DCIS have about a 98% survival rate at 10 years or more after diagnosis.
Talk with your oncology team about whether additional treatments like hormone therapy or targeted HER2 therapy might benefit you. They can assess your individual risk factors and create a personalized follow-up plan to monitor for any signs of recurrence.
January 26
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