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Radiation (20 rounds). Soon after I will meet with my oncologist to talk about Kisquali and AI's. Everything I've read about AI's talks about Estrogen suppression. Progesterone is what is feeding mine. Do you still need AI's or are there other medications for Progesterone+ breast cancer? Thanks for any help you can provide.

October 2, 2025
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For hormone receptor-positive breast cancers (including PR+), hormone therapy is typically recommended to block the effects of hormones that can fuel cancer growth. While AIs primarily target estrogen production, they are often still prescribed as part of the treatment plan for PR+ cancers, even when the cancer is ER-.

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For hormone receptor-positive breast cancers (including PR+), hormone therapy is typically recommended to block the effects of hormones that can fuel cancer growth. While AIs primarily target estrogen production, they are often still prescribed as part of the treatment plan for PR+ cancers, even when the cancer is ER-.

Treatment options for hormone receptor-positive breast cancers may include:
• Targeted therapies
• CDK 4/6 inhibitors (like Kisqali/ribociclib)
• Other hormone therapy medications It's important to discuss your specific hormone receptor status with your oncologist, as they can best determine which combination of treatments will be most effective for your particular case. They may recommend different combinations of therapies or alternative approaches based on your unique cancer profile and how you've responded to previous treatments.

October 2, 2025

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