And that is the kicker Carol. It is said if you do the 5 years, it will give another 1-2 yrs of protection when done. After that....well when estrogen comes back who knows. My suggestion when this comes up is to lose body fat since fat cells produce extra estrogen which would decrease overall estrogen in the body and then look into supplements that promote cell health so the bodies cells are in good shape and do what they are supposed to . Other than those 2 things, I just don't know.
And the supplements for cell health should begin now, not wait for 5 years

137lbs is a pretty good weight so you must be doing something right to be able to maintain that.
Yes, the 1-2 yrs of protection after AI treatment is done is only if it is taken for at least 5 years. Maybe thats how long it takes for estrogen levels to return to pre AI.

Just had this conversation with my Dr this morning. There is an additional test, similar to the Onco test that he is having done. That will tell us if I should stay on the Letrozole any longer, probably another 5 years (I’m in year 4). My breast cancer has a best chance of reoccurrence in 9 yrs. I’m on Letrozole for 5, stays in your system for approx 1 1/2-2 years. The math is sloppy on this one! We’ll see the results in about 2 weeks. 🫶

Yep @A MyBCTeam Member and its very hard to lose weight while on them. Perhaps maybe easier when the 5 yrs are done since the AI's are supposed to offer continued protection 1-2 yrs after, I think its that time if a woman wants to up her chances should consider a great weight loss program, maybe something women now could focus on as a goal.

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A MyBCTea...

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body fat does produce estrogen.
Fat cells (adipose tissue) can contribute to an increase in estrogen levels in the body, as they contain estrogen precursors that can be converted into estrogen.

Excess fat cells produce extra estrogen, which can lead to hormonal imbalances.

More body fat generally correlates with higher estrogen levels, which can have various effects on health.

Thus, maintaining a healthy body fat percentage is important for hormonal balance.