Yes, joint pain and musculoskeletal symptoms are very common side effects of aromatase inhibitors. In fact, more than half of people taking these medications experience joint pain. These symptoms are known as aromatase inhibitor-induced musculoskeletal symptoms (AIMSS). AIMSS typically appears about two months after Show Full Answer
Yes, joint pain and musculoskeletal symptoms are very common side effects of aromatase inhibitors. In fact, more than half of people taking these medications experience joint pain. These symptoms are known as aromatase inhibitor-induced musculoskeletal symptoms (AIMSS). AIMSS typically appears about two months after starting treatment and reaches its peak around four months later, though it can sometimes develop up to two years after starting treatment. The pain can affect multiple joints including hands, knees, back, hips, and shoulders. This happens because aromatase inhibitors lower estrogen levels, which can reduce bone density and increase risks of arthritis. If you're experiencing joint pain, it's important to discuss this with your doctor rather than stopping the medication on your own. They can help evaluate your options and may be able to suggest ways to manage these symptoms while maintaining your treatment.
June 24, 2025
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