MyBCTeam

The most significant side effects of anastrozole include joint pain, bone-related issues, and weight changes. Anastrozole has been shown to increase the risk of bone fractures and osteoporosis (weakened bones) more than some other similar medications. This is a serious concern that should be discussed with your healthcare Show Full Answer

The most significant side effects of anastrozole include joint pain, bone-related issues, and weight changes. Anastrozole has been shown to increase the risk of bone fractures and osteoporosis (weakened bones) more than some other similar medications. This is a serious concern that should be discussed with your healthcare provider to develop prevention strategies. Weight management can be particularly challenging while taking anastrozole. Many people experience weight gain or find it extremely difficult to lose weight while on this medication. Some MyBCTeam members report gaining significant weight (up to 35 pounds) and struggling to lose it despite following strict diets and exercise routines. This side effect tends to be most noticeable during the first year of treatment. Other common side effects include hot flashes, night sweats, vaginal dryness, and mood swings. While these side effects are significant, it's important to note that many people tolerate the medication well overall, and it remains an important treatment for hormone receptor-positive breast cancer. Always discuss any concerning side effects with your healthcare provider, as they can often help manage these symptoms.

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