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My Pathology report, after DMX, indicates pathologic complete response in breast and lymph nodes.
I don’t want to gamble with my health and may opt to receive radiotherapy - my risk preference will weigh heavily on my decision.

April 17, 2025
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A MyBCTeam Member

Well if you aren't doing radiation it would be a good time to start it. It does prevent estrogen from feeding cells .

April 17, 2025
A MyBCTeam Member

Congratulations on the complete pathological response! When they did my mastectomy, they removed the 2,7 cm tumor, and three sentinel nodes. Since the in-house pathology report showed no nasty surprises in the breast tissue removed, and the lymph nodes were clear, I was able to skip radiation. I had my surgery before chemo, and am 5 years out of active treatment, and so far, so good. The decision has to be made on your risk factors AND what will give you peace of mind.
My diagnosis was HER2+, Stage 2, Grade 3. Keeping you in prayers as you navigate through all the info to make the decisions that are right for you! Hugs!

April 17, 2025
MyBCTeam

Yes, some patients may not need radiation therapy after mastectomy, particularly when there is a complete pathologic response. The decision about whether to proceed with radiation therapy should be based on your individual circumstances, risk factors, and personal preferences.

After a total or modified radical mastectomy Show Full Answer

Yes, some patients may not need radiation therapy after mastectomy, particularly when there is a complete pathologic response. The decision about whether to proceed with radiation therapy should be based on your individual circumstances, risk factors, and personal preferences.

After a total or modified radical mastectomy, radiation therapy may be recommended if the tumor was large or if cancer cells were found in other areas of the breast, skin, or lymph nodes. However, since your pathology report shows a complete response in both breast and lymph nodes, you may fall into a category where the benefits are less clear. This is an important decision that should be made through shared decision-making between you and your healthcare team. Your approach to carefully weighing the potential benefits against your personal risk tolerance is appropriate. Remember that you have power in your treatment journey, and all decisions about your medical care should be shared by you, your family (if appropriate), and your health care team. Your doctor can help explain the specific factors in your case that might influence whether radiation therapy would be beneficial.

April 17, 2025
A MyBCTeam Member

I haven’t started an aromatase inhibitor yet…

April 17, 2025
A MyBCTeam Member

Hi Dawn, like @A MyBCTeam Member said all these treatment decisions are individual choices we have to make by putting it all together, cancer type, grade, surgeries etc. I looked at your story before answering here, you had aggressive chemo and double mastectomy, and you are on a hormone blocker. My opinion is I would skip the radiation.
Let me tell you when I met my surgeon over 2 years ago I told her no chemo. I told her it wasn't up for discussion. She said if I wasn't going to do chemo she would suggest a mastectomy. I told her that wasn't going to happen either because I planned to go right back to work so then she said radiation. I told her I would consider it. So you had both chemo and mastectomy. I would think the hormone blocker would be enough to prevent another tumor from taking hold.

April 17, 2025

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Rochester, NY