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Real members of MyBCTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

What have Kisqali short term and long term side effects been like for the community?

A MyBCTeam Member asked a question 💭
Austin, TX
April 6, 2025
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A MyBCTeam Member

Hi Sarah, I've been taking low dose (400mg, 21 days on, 7 off) since August. The biggest side effect for me has been a decreased appetite and some gastro issues similar to the AI answer, but manageable. My doctor still does regular bloodwork and so far, so good. I noticed some hair thinning at first, but it might have been a result of my hysterectomy and menopause, since everything happened around the same time. I've been using Keranique spray with positive results. I was concerned about being immunocompromised for the 3 year course of Kisqali but luckily it hasn't been an issue yet. Actually, I was one of the few amongst my coworkers that didn't get sick during flu season - go figure:)
Good luck with your new meds!

April 9, 2025
MyBCTeam

Common short-term side effects of CDK inhibitors like Kisqali (ribociclib) include diarrhea, nausea, fatigue, decreased appetite, and skin-related symptoms. Some people may experience hair thinning or loss, though this affects a minority of patients and could also be related to other factors like nutritional changes during Show Full Answer

Common short-term side effects of CDK inhibitors like Kisqali (ribociclib) include diarrhea, nausea, fatigue, decreased appetite, and skin-related symptoms. Some people may experience hair thinning or loss, though this affects a minority of patients and could also be related to other factors like nutritional changes during treatment.

More serious potential side effects that require immediate medical attention include low white blood cell counts which can increase infection risk, severe diarrhea leading to dehydration, and potential liver problems. Your healthcare team may need to adjust or pause treatment if side effects become too intense. A MyBCTeam member shared that side effects can be cumulative, meaning they may build up over time with continued treatment. Recovery time between treatments may also increase as you progress through your treatment course. It's important to keep your healthcare team informed about any side effects you experience so they can help manage them effectively.

April 6, 2025

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