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I am 70 years old with lobular cancer including 9 positive lymph nodes. I had a partial mastectomy, lymph node removal, breast reduction and radiation. Before the surgery I was on Anastrozole and Verzenio for 6 months. Now I am on Anastrozole and Kisqali. For me, the Kisqali (so far) has been better tolerated. I have been on it for over a week, and I have not noticed any major side-effects. On the Verzenio, I had diarrhea and fatigue.
I have been on Kisqali since February 2025. I felt the worst the first
month. I was fatigued and achey; I had a low grade fever. It correlated
with a low white blood cell (WBC) count. After that, the side-effects were
less intense.
I was initially on Kisqali 400 mg, but the dose was finally decreased to
200 mg daily because of my WBC counts. When I take the Kisqali, I feel
fatigued, my brain is fuzzy, and I have less patience with people. I look
forward to the 7 days each month when I can stop the medication.
I am also on Anastrazole 1 mg daily. I attribute my thinning hair and
drying skin to that.
Overall I rather be on Kisqali than Verzenio.
Best wishes for the good health and even better spirits,
Barbara
Update: i just finished my first 3 weeks of Kisqali. (I am also on Anastrozole.) The first 2 1/2 weeks were great. At the end of the 3rd week, I was achy all over with decreased appetite and fatigue. Last night my temperature increased to 99.3 for a few hours. The doctor said I should start feeling better during the off week.
It's great to hear that you're tolerating Kisqali well so far! Kisqali (Ribociclib) is often used in combination with hormone therapy like Anastrozole for hormone receptor-positive breast cancer. While some people experience side effects like fatigue, nausea, or changes in blood counts, others tolerate it better than Show Full Answer
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