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A MyBCTeam Member asked a question 💭
Hamilton, ON

I am nervous about starting a new cycle of chemotherapy that involves Paclitaxel, Trastuzumab and Perjeta (Pertuzumab) for IDC breast cancer (her2+, Estrogen+).

Does anyone have practical advice or experience to share?

October 22, 2023
 · 
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A MyBCTeam Member

Taxol is not too bad. Biggest side effect to watch for is neuropathy in your hands and feet. Some do ice mitts/socks during infusion to try to prevent. Trastuzumab and Pertuzumab, called HP are immunotherapy. Herceptin is usually tolerated well. A heart echo should be done before starting to check your heart. Perjeta can be a jerk! Biggest side effect diahhrea. Have Imodium on hand. If that doesn’t work, tell your doctor, they can prescribe Lomotil. Make sure you are drinking Gatorade, or similar for lost fluids and electrolytes.
Drink as much water as you can, eat when you can, sleep when you need to, be as active as possible and let your doctor know if you are struggling. Extra IV fluids can really help!
Wishing you well!

October 22, 2023
A MyBCTeam Member

I was treated with Carboplatin and Doxetal chemo drugs, and Herceptin and Perjeta targeted drugs for HER2 Pos breast cancer. The side effects from the targeted drugs were minimal and I was on them for 1 year. The 6 cycles of the chemo drugs were a bit harsher, but were manageable with anti nausea, anti diarrheal medication as needed, and anti anxiety drugs. The main thing is to go easy on yourself. I only had one day that I went back to bed because I was more tired than usual. I took Zofran every eight hours for the first week after chemo to avert any nausea. If you don't feel like eating, don't fret over it, but stay hydrated and use those electrolyte powders you can put in bottled water.

October 22, 2023
A MyBCTeam Member

I had Taxotere (same family of drugs as Paclitaxol) Carboplatin, and Herceptin (trastuzumab), 6 sessions at 3 weeks apart. Rest when your body tells you to, eat healthy, get some movement in every day (walking is great) and hydrate!! On chemo days I ate breakfast, usually scrambled eggs with cheese, which is light proteins to stick with me, since my chemo session ran from 8-4 the first time. I packed a few snacks I knew I'd like, and of course, the water bottle! For me, light snacky type meals worked better than heavier ones, staying away from fried foods, or greasy things- really helped keep the tummy flutters away. I kept packs of crackers around, along with Ginger Ale, and Gin-Gin candies, since ginger is a natural tummy soother. My biggest side effect was the fatigue brought on by the Taxotere, but Paclitaxol is supposed to be much kinder! Keeping you in prayers for all the best with your new protocols! Hugs!

October 22, 2023
A MyBCTeam Member

I was on docetaxel, carboplatin, and herceptin, 6 rounds, 3 weeks between each round.
My oncologist gave me both compro and zofran for nausea. I usually took one of them the morning of infusions and for about 3-4 days following each. That was usually enough to keep the nausea to a minimum. I did throw up once, after infusion #5.
I would suggest asking for anti nausea meds and taking them for at least the first 3 days after each infusion.
Also, lots of water and Gatorade. And protein. If you aren't up for eating, get protein shakes. You need to keep your body as healthy as possible to counteract the chemo effects.
Good luck!

October 23, 2023
A MyBCTeam Member

Thank you 🙏 This is so helpful.

October 22, 2023

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