I am fortunate enough to have spoken with several top docs in the country due to the nature of my job, I am also ER/PR neg and HER2 positive. My oncologist, my breast surgeon and the opinion of several other doctors is 12 months of Herceptin. I had a lumpectomy last month and I start chemo with Taxotere, Carboplatin and Herceptin 6 rounds and I'll continue with the Herceptin for a full 12 months.

I did Taxotere, carboplatin and Herceptin for 8 rounds then a year of herceptin and perjeta after mastectomy. On my last treatment June 30th.

As far as i know tamoxifen is only useful for er + cancer ie hormonal cancers. Since yours is negative it is pointless as it works by blocking the hormone receptors that cause the cancer.

You need your slides sent to a good center. They will re-examine them and determine what exactly you have. It sounds like you need it all -THP and tamoxifen after. Her2+ in a node is concerning and you may need radiation too. There are centers under www.nccn.org Get on the closest ones website and request a video consult. It is amazing how good they are at this now. You could also chose one far away for consult. I would do this. They will look at your slides, etc. and make recommendations based on standards. You also may qualify for a clinical trial. I did this once for an ovarian mass--shipped the slides off to John Hopkins and their lab looked at it and said it was ok. My insurance even paid for it.

I had a lumpectomy, onco type low.one lymph node poss. now on Letrozole.