I don't have that answer but based on many comments here, some people have better luck (less side effects) with one AI vs another. I take letrozole and had hip and leg pain (pretty bad) but it got much better after 6 months. I also have hot flashes but I had those since chemo. I also have NOT gained weight. Best of luck with your decision.

Well I was on Arimidex for a year, could not take it anymore. Now some people are ok on it, as for me the side effects were absolutely brutal. I became an angry, mean person and because of the numerous side effects I no longer have my girls in my life. They did not like the person I became and told me when I was off the drug to contact them. I am on tamoxifen now and do find it somewhat better than arimidex however depending on your cancer the doctor prescribes accordingly. I was told by my oncologist that if I went off the arimidex I would up my chances of recurrence and he could not promise me it would not come back however I wanted quality of life over quantity the side effects for me were that horrible. So I went off of it and am now on tamoxifen. BTW I still don't have my kids in my life, I figure if they can't handle me at my worst then they sure as hell don't deserve me at my best....... I sure didn't give up on them when they were teenagers and I didn't like there attitudes...... good luck on your decision..... and survival....

I've been taking Arimidex since November as well as getting Lupron injections bi-monthly... The only side effects are hot flashes and some vaginal dryness. No weight gain or any other pains.

I have been taking Arimidex for a little over 1 month and no side effects yet. Knock on wood!

I have been on for 2 and 1/2 months and don't really notice anything yet.