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I have been taking tamoxifen for 2 1/2 years on and off. I have had many side effects and it seriously got so bad I thought I would lose my job. I was placed on Effexor generic low dose 37.5 mg 2x a day. It has helped as I had severe anxiety and insomnia. I just recently started back on the tamoxifen after a 2 month holiday and after 3 weeks I'm suffering from severe fatigue and my mood has plummeted! Ugh

June 17, 2014 (edited)
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A MyBCTeam Member

Are there any studies determining the effectiveness of a lower dosage of Tamoxifen? I quit Tamoxifen after learning it was only benefitting me 1%. Ask your doctor to run the serious numbers for your particular case. You deserve to make an honest educated decision as to whether or not you stay on this drug. Ask him to run New Adjuvant Online dot Com for you. It sealed the deal for me!

June 18, 2014
A MyBCTeam Member

Hotflashes! Now it just helps me not feel so stressed! I work full-time and go to school! It helps alot.

March 21, 2015
A MyBCTeam Member

10mg of Tamoxifen is the lowest dose. I was on 10mg of Tamoxifen daily until I had my prophylactic total hysterectomy and bilateral oopherectomy and my anti-hormonal medication was switch to Femara which is 2.5mg.

June 18, 2014
A MyBCTeam Member

I take 20mg and 75 of effexor. Going to stop the effexor it was for my hot flashes and really hasn't helped that much. So when I go to Gyno next week that will be the discussion to at least go back to 37.5

June 18, 2014
A MyBCTeam Member

I take 20 mg tamoxifen once a day with 75 mg effexor twice a day which has helped tremendously. My onc started me on 37.5 mg twice a day but increased it after a month when it wasn't helping enough. See if your onc will increase your effexor....

June 17, 2014

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