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A MyBCTeam Member asked a question 💭
Sandpoint, ID

I am scheduled to do a hysterectomy because the Tamoxifin isn't stopping my estrogen production and I'm ER+PR+HER2+ Has anyone else had to have their ovaries out or have a hysterectomy to fight breast cancer?

August 9, 2012
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A MyBCTeam Member

Tamoxifen does not stop the estrogen production. This is a myth. Tamoxifen is designed to stop the receptors from receiving estrogen. The only drugs that stop estrogen production are the post menopausal class of drugs called aromotase inhibitors. ask your doctor to sit down and go over with www.newadjuvantonline.com with you to see how Tamoxifen does or does not benefit you. It only gave me a 1% benefit so I quit and never looked back.

August 20, 2012 (edited)
A MyBCTeam Member

Actually Tamoxifen suppressed estrogen receptors to the breast but theres not affect to the ovaries that continue to produce estrogen. I had a total hysterectomy and bilateral saling-oophectomy for the peace of mind.

March 2, 2013 (edited)
A MyBCTeam Member

after a year of tamoxifen, I underwent a hysterectomy because of early stages of uterine cancer. I was switched to Letrozole (Femara). My painful spasms have lessened on the newer med.

August 21, 2012 (edited)
A MyBCTeam Member

I was on Tamoxifen and had to have a hysterectomy. My PAP showed hyperplasia (MILD), and at first they said it was tamoxifen effect on the cells, but a follow up PAP a year later showed progressing hyperplasia(MODERATE) so they recommended a hysterectomy.

I completed the 5 years on tamoxifen. But the first questionable PAP was during the last year of treatment. They tried me off the tamoxifen to see if it would improve the PAP, but my estrogen results were off the chart and they decided to put me back on the tamoxifen. Then the second PAP results came back with worsening hyperplasia. I had the surgery last summer. Not exactly what you were asking but if you have any questions, I'd be glad to help with any.

August 11, 2012 (edited)
A MyBCTeam Member

Rule back in 2001 when I was first dx with breast cancer, I had a mastectomy with TRAM (where the take the fat from the abdomen and build a breast with that fat - as long as you have enough fat). But the rule at the hospital in MI I received my treatment a hysterectomy wasn’t a question, you have it. I didn’t have a problem because I gave birth to my second son in 1997 who happened to be 7 1/2 weeks early and was an infertility baby. One year later my physician explained to my then husband I probably would not ever be able to carry and give birth because of the condition of my uterus, h said it was like a ‘BIG BLOB’, that’s why my periods were so long and heavy and strongly suggested it would be in my best interest to have a hysterectomy, so I did and was DX with breast cancer 1.5 years ago (2001). My oncologist did ask me if I has a hysterectomy because if not I would have to have a total prior to going on Tamoxifin. So I strongly believe it’s a standard rule. If you have any further questions I think you’d be better off sitting down with your physician! GOOD LUCK

August 10, 2012 (edited)

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