ESTROGEN RECEPTOR AGONISTS
Faslodex is a prescription drug approved by the Food and Drug Administration (FDA) in 2002 to treat estrogen receptor-positive breast cancer in postmenopausal women whose cancer progressed after treatment with antiestrogen therapy such as Tamoxifen. Faslodex is also known by its drug name, Fulvestrant.
Faslodex is not suitable for women of childbearing age or those who have shown hypersensitivity to Fulvestrant. Faslodex should be used with caution in women with a history of bleeding disorders or liver problems.
About two-thirds of breast cancers are estrogen receptor-positive, meaning that they require estrogen in order to grow. Faslodex is a member of a class of drugs called estrogen receptor agonists. Faslodex is believed to work by blocking estrogen from acting on breast cancer cells, thereby slowing the growth of the cancer.
How do I take it?
Faslodex is taken as an intramuscular injection administered in a clinical setting by a doctor or nurse. When you begin taking Faslodex, you will need to receive three injections in the first month as a loading dose. After the first month, Faslodex is taken once a month. Each dose consists of two injections, one in each buttock.
You may need to take Faslodex for several years.
Always follow your doctor’s instructions exactly when taking Faslodex.
Fulvestrant (Faslodex) was approved in 2002 based on clinical trial results that showed it to be at least as effective as Anastrozole at controlling the progression of breast cancer that spread after antiestrogen therapy.
Common side effects of Faslodex include hot flashes, dizziness, weakness, nausea, vomiting, constipation, loss of appetite, pain in bones and joints, unusual sweating, arthritis, headache, depression, and peripheral edema (swelling of the lower legs and feet).
Many drugs can cause allergic reactions, which, in the most serious cases, can result in death. Seek immediate medical help if you experience signs of a severe allergic reaction such as chest pain, itching, hives, difficulty breathing or swelling in the face, throat, eyes, lips, or tongue.
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