Ibrance (palbociclib) is a CDK inhibitor used to treat certain types of breast cancer. Like all medications, it can cause side effects — some common, some more serious.
Here are the most frequently reported side effects:
- Fatigue — feeling deeply tired, even after rest
- Nausea
- Diarrhea or constipation
- Hair thinning Show Full Answer
Ibrance (palbociclib) is a CDK inhibitor used to treat certain types of breast cancer. Like all medications, it can cause side effects — some common, some more serious.
Here are the most frequently reported side effects:
- Fatigue — feeling deeply tired, even after rest
- Nausea
- Diarrhea or constipation
- Hair thinning or hair loss
- Infections — due to low white blood cell counts (neutropenia)
- Abdominal pain
- Decreased appetite
Some more serious side effects to watch for include:
- Severe infections — low white blood cell counts can make you more vulnerable
- Severe diarrhea — can lead to dangerous dehydration
- Liver problems
- Blood clots
- Allergic reactions — such as hives, trouble breathing, or swelling
- Chest pain
It's also not safe to take during pregnancy or while breastfeeding.
If any side effects feel unmanageable or you notice something new or worsening, reach out to your care team right away. They may adjust your dose or suggest ways to help manage what you're experiencing. You know your body best!
AI-generated responses are not a substitute for medical advice. These services are not intended to
diagnose, treat, or cure any condition or disease. Always ask your doctor about specific health concerns.
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