Aromasin (exemestane) is an aromatase inhibitor used to help reduce the risk of hormone receptor-positive breast cancer coming back. Like all aromatase inhibitors, it comes with a range of side effects worth knowing about.
Here are the most common ones:
- Bone and joint pain – stiffness, soreness, and weakness in joints Show Full Answer
Aromasin (exemestane) is an aromatase inhibitor used to help reduce the risk of hormone receptor-positive breast cancer coming back. Like all aromatase inhibitors, it comes with a range of side effects worth knowing about.
Here are the most common ones:
- Bone and joint pain – stiffness, soreness, and weakness in joints like hands, knees, hips, and shoulders
- Bone loss (osteoporosis) – reduced bone density, which can increase fracture risk
- Hot flashes – a very common menopausal-type symptom
- Fatigue – feeling unusually tired
- Headache or dizziness
- Digestive changes – nausea, constipation, diarrhea, or loss of appetite
- High cholesterol – Aromasin can affect cholesterol levels
- Weight changes – some people notice weight gain during treatment
- Sleep disruption – difficulty falling or staying asleep Some rarer but more serious side effects to watch for include hives, breathing problems, fever, unusual bleeding or bruising, swelling, or changes in mental health. If any of these occur, contact your doctor right away.
It's really important never to stop taking Aromasin without speaking to your care team first — they can help find ways to manage side effects or explore alternatives if needed.
May 7
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