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A MyBCTeam Member asked a question 💭
Mt Shasta, CA

It responded to prednisone 5 mg daily. too many side effects though. Started PEMF and now neutropenia gone by itself?!

April 3
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MyBCTeam

How did your neutropenia resolve after immune checkpoint inhibitor treatment?

It's encouraging that your neutropenia has improved! Immune checkpoint inhibitors like pembrolizumab can cause autoimmune reactions where your immune system attacks healthy cells, including those that produce white blood cells. These reactions Show Full Answer

How did your neutropenia resolve after immune checkpoint inhibitor treatment?

It's encouraging that your neutropenia has improved! Immune checkpoint inhibitors like pembrolizumab can cause autoimmune reactions where your immune system attacks healthy cells, including those that produce white blood cells. These reactions can sometimes occur weeks or even months after treatment ends.

Prednisone and other corticosteroids are commonly used to manage immune-related side effects from checkpoint inhibitors because they suppress the immune system's overactive response. While you experienced too many side effects from prednisone, it may have helped calm the autoimmune reaction initially.

Regarding your recovery:

It's possible that your neutropenia resolved on its own as your immune system gradually rebalanced after the checkpoint inhibitor effects wore off. Some immune-related side effects do improve over time without ongoing treatment.

However, PEMF (pulsed electromagnetic field therapy) isn't established as a treatment for immune checkpoint inhibitor-related neutropenia in breast cancer care. Your improvement is more likely related to:

- Natural resolution of the immune reaction over time
- Lingering effects of the prednisone you took
- Your body's immune system returning to normal function

Important: Make sure to keep your oncology team informed about your neutrophil counts and any complementary therapies you're using, so they can monitor your blood counts and overall health appropriately.

April 3

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