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A new study shows that targeting key epigenetic proteins may permanently switch off cancer genes.

Scientists at Monash University, working with Harvard University, report they have found a way to permanently ‘switch off’ genes that help cancers survive. If the approach holds up in further testing, it could point to a new style of treatment that works with shorter courses and fewer of the harsh side effects that often come with long, continuous cancer therapy.

February 19
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Answer Summary

Members expressed excitement and gratitude about the scientific breakthrough showing that targeting key epigenetic proteins may permanently... Read more

Members expressed excitement and gratitude about the scientific breakthrough showing that targeting key epigenetic proteins may permanently switch off cancer genes, with many hopeful about the possibility of shorter treatment courses and reduced side effects. Several members shared appreciation for the information, with one clarifying that the research originated from a leukemia study but has promising implications for all cancer patients. A recurring theme was the importance of continued research funding and prayers for the success of this approach in future testing.

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How does this relate to current breast cancer treatments?

This research on switching off cancer genes represents an exciting potential advancement in how breast cancer might be treated in the future. Currently, many breast cancer treatments work by blocking proteins or hormones that help cancer cells grow, but they don't Show Full Answer

How does this relate to current breast cancer treatments?

This research on switching off cancer genes represents an exciting potential advancement in how breast cancer might be treated in the future. Currently, many breast cancer treatments work by blocking proteins or hormones that help cancer cells grow, but they don't permanently turn off the genes themselves.

For example, hormonal therapies block estrogen receptors on cancer cells, and targeted therapies interfere with proteins like HER2. These treatments often need to be taken continuously for years—sometimes up to 10 years after surgery—to prevent cancer from returning.

If this new approach proves effective for breast cancer, it could mean:
- Shorter treatment courses instead of years-long therapy
- Potentially fewer side effects from continuous medication
- A more permanent solution by targeting the genetic "switches" that keep cancer cells alive

However, this research is still in early stages. Current proven treatments remain the standard of care, and any new approach would need extensive testing specifically in breast cancer patients before becoming available.

It's worth discussing with your oncologist how emerging research might eventually impact your treatment options, while focusing on the effective therapies available now.

February 19
A MyBCTeam Member

Prayers it works.

February 26
A MyBCTeam Member

This is why funding cancer research is so important!!!

February 23
A MyBCTeam Member

could you please provide the link where we can read about it. Thanks....great news!!!

February 20
A MyBCTeam Member

What a wonderful advance this will be. Prayers for continued research.

February 20

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