I'm sorry. You are only DCIS ? and you did all that? Did your oncologist explain why she wants you on the new med? Personally, mastectomy, chemo, radiation and 7 years on Anastrozole should be enough. Really depends on why your doctor wants you to take Ribociclib.

Ribociclib is a targeted treatment used to treat breast cancer that is hormone receptor-positive, HER2-negative breast and has spread (metastasized) or cannot be removed by surgery.

I see. I understand better now. I remember my surgeon thought my tumor was close to the chest wall and she explained if it was she wouldn’t be able to remove the part attached to the chest wall but luckily it wound up not being so . So, since your surgeon couldn’t remove yours I still would think the radiation killed any cancer cells left behind. I had 3 separate radiation to 3 different bone Mets 2 yrs, 1 yr and a few months ago . The treatments were 5 in a row for the first two and 3 for the last one and the cancer was killed in each spot and remain stable . The decision is yours alone . You could try the lower dose for a while but if you really can’t tolerate don’t force yourself to stay on it .

Hopefully the time off will allow your labs to all go back within the normal range.
She did cut the dosage in half from what you were taking before.
Ask when they will run labs again with this new dose so that if things are headed in the wrong direction it can be quickly caught, and everything reevaluated.
Keeping you in prayers for better labs, and in navigating through all the info to make the decisions that are right for you! Hugs!

I guess I forgot... I did forget... my doctor wanted me to take ribociclib because I had a total bilateral mastectomy with sentinel lymph node biopsy and out of three removed lymph nodes, 1 was positive for cancer and there was a spot in/on my chest muscle that they couldn't/ can't remove, so I was surgery, chemo and radiation for me, but that's the reason my doctor wanted me to take ribociclib.